 |
Common Tradename
 |
GARAMYCIN |
|
 |
Class
 |
aminoglycoside |
|
 |
Dosage, Adult (usual)
 |
IM or IV 3-6mg/kg/day (divided Q8H) or 4-7mg/kg/day Q24H |
 |
OPTH apply oint BID-TID or instill soln 1-2 drops Q2-4H |
|
 |
Dosage, Pediatric, (usual)
 |
2.5-3.5mg/kg/dose IV or IM Q8H |
|
 |
Dose Adjustments:
 |
geriatrics |
 |
renal impairment |
|
 |
Administration
 |
dilute in 50-200mL NS or D5W, infuse over 30-120min |
|
 |
How Supplied
 |
0.3% OPHTHALMIC OINTMENT |
 |
0.3% OPHTHALMIC SOLUTION |
 |
10 MG/ML, 40 MG/ML SOLUTION FOR INJECTION |
|
 |
Indications
 |
susceptible bacterial infections |
|
 |
Contraindications
 |
hypersensitivity to gentamicin |
|
 |
Adverse Effects
 |
nephrotoxicity |
 |
ototoxicity |
|
 |
Drug Interactions
 |
bumetanide |
 |
capreomycin |
 |
carboplatin |
 |
cephalosporins |
 |
cidofovir |
 |
cyclosporine |
 |
ethacrynic acid |
 |
furosemide |
 |
indomethacin |
 |
magnesium |
 |
methoxyflurane |
 |
nondepolarizing neuromuscular blockers |
 |
piretanide |
 |
polygeline |
 |
succinylcholine |
 |
tacrolimus |
 |
typhoid vaccine |
 |
vancomycin |
|
 |
Pregnancy Category
 |
D |
|
 |
Breast Feeding
 |
controversial |
|
 |
Notes
 |
use IBW for dosage |
|