|
Common Tradename
|
GARAMYCIN |
|
|
Class
|
aminoglycoside |
|
|
Dosage, Adult (usual)
|
IM or IV 3-6mg/kg/day (divided Q8H) or 4-7mg/kg/day Q24H |
|
OPTH apply oint BID-TID or instill soln 1-2 drops Q2-4H |
|
|
Dosage, Pediatric, (usual)
|
2.5-3.5mg/kg/dose IV or IM Q8H |
|
|
Dose Adjustments:
|
geriatrics |
|
renal impairment |
|
|
Administration
|
dilute in 50-200mL NS or D5W, infuse over 30-120min |
|
|
How Supplied
|
0.3% OPHTHALMIC OINTMENT |
|
0.3% OPHTHALMIC SOLUTION |
|
10 MG/ML, 40 MG/ML SOLUTION FOR INJECTION |
|
|
Indications
|
susceptible bacterial infections |
|
|
Contraindications
|
hypersensitivity to gentamicin |
|
|
Adverse Effects
|
nephrotoxicity |
|
ototoxicity |
|
|
Drug Interactions
|
bumetanide |
|
capreomycin |
|
carboplatin |
|
cephalosporins |
|
cidofovir |
|
cyclosporine |
|
ethacrynic acid |
|
furosemide |
|
indomethacin |
|
magnesium |
|
methoxyflurane |
|
nondepolarizing neuromuscular blockers |
|
piretanide |
|
polygeline |
|
succinylcholine |
|
tacrolimus |
|
typhoid vaccine |
|
vancomycin |
|
|
Pregnancy Category
|
D |
|
|
Breast Feeding
|
controversial |
|
|
Notes
|
use IBW for dosage |
|