|
Common Tradename
|
AMIKIN |
|
|
Class
|
aminoglycoside |
|
|
Dosage, Adult (usual)
|
IV/IM 7.5mg/kg Q12H or 5mg/kg Q8H; MAX 1.5g/day |
|
|
Dosage, Pediatric, (usual)
|
IM/IV 7.5mg/kg Q12H or 5mg/kg Q8H; MAX 1.5g/day |
|
newborns IM/IV Loading dose 10mg/kg, then 7.5mg/kg Q12H |
|
|
Dose Adjustments:
|
renal impairment |
|
|
Administration
|
IV over 30 min, infants infuse over 1-2 hr |
|
|
How Supplied
|
1 G/4 ML, 500 MG/2 ML SOLUTION FOR INJECTION |
|
|
Indications
|
susceptible bacterial infections |
|
|
Contraindications
|
hypersensitivity to amikacin products |
|
|
Adverse Effects
|
nephrotoxicity |
|
ototoxicity |
|
|
Drug Interactions
|
bumetanide |
|
capreomycin |
|
carboplatin |
|
cephalosporins |
|
cidofovir |
|
colistin |
|
cyclosporine |
|
ethacrynic acid |
|
furosemide |
|
indomethacin |
|
magnesium |
|
methoxyflurane |
|
nondepolarizing neuromuscular blockers |
|
piretanide |
|
succinylcholine |
|
tacrolimus |
|
typhoid vaccine |
|
vancomycin |
|
|
Pregnancy Category
|
D |
|
|
Breast Feeding
|
safe |
|