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TOBRAMYCIN

Common Tradenames
NEBCIN
TOBREX
Class
aminoglycoside
Dosage, Adult (usual)
IM/IV 3-6mg/kg/day (divided Q8H), IV 4-7mg/kg/day Q24H
OPTH apply oint BID-TID, instill solution 1-2drops Q2-4H
Dosage, Pediatric, (usual)
IM/IV 2.5-3.5mg/kg/dose Q8-24H
OPTH apply oint BID-TID, instill solution 1-2drops Q2-4H
Dose Adjustments:
renal impairment
How Supplied
40 MG/ML INJECTION
3 MG/G OPHTHALMIC OINTMENT
3 MG/ML OPHTHALMIC SOLUTION
20 MG/2 ML PEDIATRIC SOLUTION FOR INJECTION
Indications
susceptible bacterial infections
Contraindications
hypersensitivity to tobramycin or other aminoglycosides
Adverse Effects
nephrotoxicity
ototoxicity
Drug Interactions
bumetanide
capreomycin
carboplatin
cephalosporins
cidofovir
cisplatin
cyclosporine
ethacrynic acid
furosemide
indomethacin
magnesium
nondepolarizing neuromuscular blockers
piretanide
succinylcholine
tacrolimus
typhoid vaccine
vancomycin
Pregnancy Category
D
Breast Feeding
safe

REFERENCE: MICROMEDEX(R) Healthcare Series Vol. 111 expires 3/2002

DESIGNED BY HASHIM TAYEB (Bsc PHARM)