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PROCAINAMIDE HYDROCHLORIDE

Common Tradenames (See Complete Tradename Listing)
PROCAN SR
PROCANBID
PRONESTYL
Class
antiarrhythmic, group ia
Dosage, Adult (usual)
50mg/kg PO DAILY (divide Q6-12H)
IV initial MAX rate 50mg/min up to MAX dose of 1gram, then maintenance infusion 2-6mg/min
Dosage, Pediatric, (usual)
50-125mg/kg PO DAILY (divide Q3-6H); MAX dose 4G/day
IV 10-15mg/kg over 15min then 20- 80mcg/kg/min OR 50-100mg/kg/24hr(divided Q4h); MAX 2G/24h
Dose Adjustments:
liver disease, renal impairment
How Supplied
250 MG, 375 MG, 500 MG CAPSULE
1000 MG, 500 MG EXTENDED-RELEASE TABLET
1000 MG, 250 MG, 500 MG, 750 MG SUSTAINED-RELEASE TABLET
Indications
arrhythmias
Contraindications
hypersensitivity to procainamide, procaine/local anesthetics
heart block
SLE
Torsades de Pointes
Adverse Effects
myelosuppression
neuropathy
SLE
N/V
diarrhea
dizziness
Drug Interactions
acecainide
alcuronium
amiodarone
atracurium
bepridil
cimetidine
cisapride
cisatracurium
disopyramide
distigmine
dofetilide
dolasetron
doxacurium
gallamine
gatifloxacin
grepafloxacin
halofantrine
hexafluorenium bromide
ibutilide
levofloxacin

 

levomethadyl
mesoridazine
metformin
metocurine
mivacurium
moricizine
moxifloxacin
pancuronium
pimozide
pipecuronium
pirmenol
prajmaline
quinidine
rapacuronium
rocuronium
sotalol
sparfloxacin
succinylcholine
trimethoprim
tubocurarine
vecuronium

 

Pregnancy Category
C
Breast Feeding
controversial

REFERENCE: MICROMEDEX(R) Healthcare Series Vol. 111 expires 3/2002

DESIGNED BY HASHIM TAYEB (Bsc PHARM)