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DIGOXIN

Common Tradename
LANOXIN
Class
digitalis glycoside
Dosage, Adult (usual)
PO/IV loading range 8-12mcg/kg, PO maintenance 0.125-0.5mg/day
Dosage, Pediatric, (usual)
maintenance doses range 5-10mcg/kg PO/IV depending on age and response
Dose Adjustments:
renal impairment
geriatrics
Administration
IV bolus doses over at least 5min
How Supplied
0.25 MG /ML INJECTION
0.125 MG, 0.25 MG, 0.5 MG TABLET
Indications
CHF
supraventricular arrhythmias
Contraindications
hypersensitivity to digoxin products
ventricular fibrillation
Adverse Effects
N/V
visual disturbances
headache
arrhythmias
anorexia
Drug Interactions
acarbose
acetazolamide
activated charcoal
alprazolam
aluminum carbonate, basic
aluminum hydroxide
aluminum phosphate
amiloride
aminosalicylic acid
amiodarone
amphotericin b
amphotericin b cholesteryl sulfate complex
amphotericin b lipid complex
amphotericin b liposome
arbutamine
atorvastatin
azithromycin
azosemide
bepridil
beta-adrenergic blockers
buckthorn
bumetanide
calcium
canrenoate
carbimazole
cascara sagrada
cholestyramine
clarithromycin
colestipol
cyclophosphamide
cyclosporine
dalfopristin
diazepam
diclofenac
dihydroxyaluminum aminoacetate
dihydroxyaluminum sodium carbonate
diltiazem
dirithromycin
disopyramide
erythromycin
ethacrynic acid
flecainide
fluoxetine
furosemide
gatifloxacin
hydroxychloroquine
indecainide
indomethacin
itraconazole
kaolin
khella
kyushin
lornoxicam
magaldrate
magnesium carbonate
magnesium hydroxide
magnesium oxide
magnesium trisilicate
metformin
methimazole
metoclopramide
mibefradil
midodrine
nefazodone
neomycin
nifedipine
nilvadipine
nisoldipine
nitrendipine
omeprazole
vincristine
pancuronium
paromomycin
penicillamine
piretanide
propafenone
propantheline
quinidine
quinine
quinupristin
rabeprazole
rifampin
roxithromycin
simvastatin
spironolactone
st john's wort
succinylcholine
sucralfate
sulfasalazine
telmisartan
tetracycline
thiazide diuretics
torsemide
tramadol
trimethoprim
valspodar
verapamil
Pregnancy Category
C
Breast Feeding
safe

REFERENCE: MICROMEDEX(R) Healthcare Series Vol. 111 expires 3/2002

DESIGNED BY HASHIM TAYEB (Bsc PHARM)