 |
Common Tradename
 |
CHLOROMYCETIN |
|
|
Class
|
antibiotic |
|
|
Dosage, Adult (usual)
|
50-100mg/kg/day IV (divide Q6H) |
|
|
Dosage, Pediatric, (usual)
|
50-100mg/kg/day IV(divide Q6H) |
|
|
Dose Adjustments:
|
renal impairment |
|
liver disease |
|
|
Administration
|
adjust dose based on serum levels |
|
|
How Supplied
|
1 G INJECTION |
|
1 GRAM/10 ML POWDER FOR INJECTION |
|
|
Indications
|
Bacteroides, H influenzae |
|
N meningitidis, Salmonella |
|
rickettsial infections |
|
lymphogranuloma-psittacosis group |
|
gram-negative bacteremia |
|
|
Contraindications
|
hypersensitivity to chloramphenicol products |
|
|
Adverse Effects
|
N/V |
|
irreversible aplastic anemia |
|
rash |
|
myelosuppression |
|
gray baby syndrome (children) |
|
|
Drug Interactions
|
ceftazidime |
|
chlorpropamide |
|
cyclophosphamide |
|
cyclosporine |
|
dicumarol |
|
entacapone |
|
fosphenytoin |
|
glimepiride |
|
phenobarbital |
|
phenytoin |
|
rifampin |
|
tacrolimus |
|
tetanus toxoid |
|
tolbutamide |
|
typhoid vaccine |
|
warfarin |
|
|
Pregnancy Category
|
C |
|
|
Breast Feeding
|
unsafe |
|
|
Notes
|
not first-line agent/no prophy role |
|
