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CARBAMAZEPINE

Common Tradenames
CARBATROL
TEGRETOL
TEGRETOL-XR
Class
anticonvulsant
central nervous system
neurogenic diabetes insipidus
Dosage, Adult (usual)
epilepsy initial 200mg PO BID or 100mg QID (susp); maintence 800-1200mg/day (divide BID-QID); MAX 1600mg/day
trigeminal neuralgia initial 100mg PO BID or SR 200mg QD or 50mg (susp) QID; maintenance 400-800mg/day; MAX 1200mg/day
bipolar disorder 600-1600mg/day in divided doses, up to 3000mg/day
Dosage, Pediatric, (usual)
epilepsy (under 6yrs) 10-20mg/kg/day (divide BID-QID); MAX 35mg/kg/day
epilepsy (6-12yrs) 100mg PO BID or 50mg (susp) QID, maintenance 400-800mg/day; MAX 1g/day
epilepsy (over 12yrs) 200mg PO BID or 100mg (susp) QID, maintenance 800-1000mg/day; MAX 1000-1200mg/day
Administration
administer tablets and extended release tablets BID and suspension QID
take with food
How Supplied
100 MG CHEWABLE TABLET
300 MG EXTENDED-RELEASE CAPSULE
100 MG, 200 MG, 400 MG EXTENDED-RELEASE TABLET
100 MG/5 ML ORAL SUSPENSION
200 MG TABLET
Indications
epilepsy
trigeminal neuralgia
bipolar disorder
Contraindications
hypersensitivity to carbamazepine products
bone marrow suppression
hypersensitivity to any tricyclic compound
Adverse Effects
nausea
drowsiness
dizziness
ataxia
blood dyscrasias
Drug Interactions
acetaminophen
acetylcysteine
activated charcoal
adenosine
alprazolam
amitriptyline
amoxapine
amprenavir
anisindione
atracurium
betamethasone
caspofungin
cimetidine
cisplatin
clarithromycin
clomipramine
clonazepam
clorgyline
clozapine
cortisone
cyclosporine
dalfopristin
danazol
dehydroepiandrosterone
delavirdine
desipramine
dexamethasone
dicumarol
diltiazem
dothiepin
doxacurium
doxepin
prednisolone
prednisone
primidone
doxorubicin
doxorubicin hydrochloride liposome
doxycycline
erythromycin
ethinyl estradiol
ethosuximide
etretinate
evening primrose oil
felbamate
fluconazole
flunarizine
fluoxetine
fluvoxamine
fosphenytoin
ginkgo
haloperidol
hydrochlorothiazide
hydrocortisone
imipramine
indinavir
influenza virus vaccine
iproniazid
isocarboxazid
isoniazid
itraconazole
ketoconazole
lamotrigine
levonorgestrel
lithium
loxapine
mebendazole
mestranol
methylphenidate
methylprednisolone
metronidazole
mianserin
midazolam
miokamycin
moclobemide
nafimidone
nefazodone
nelfinavir
niacinamide
nialamide
norethindrone
norgestrel
nortriptyline
olanzapine
omeprazole
pancuronium
pargyline
pentobarbital
phenelzine
phenobarbital
phenprocoumon
phenytoin
pipecuronium
praziquantel
procarbazine
propoxyphene
protriptyline
psyllium
quinupristin
remacemide
rifampin
risperidone
ritonavir
rocuronium
sabeluzole
saquinavir
selegiline
sertraline
st john's wort
tacrolimus
terfenadine
theophylline
tiagabine
ticlopidine
toloxatone
topiramate
tramadol
tranylcypromine
trimipramine
troleandomycin
valnoctamide
valproic acid
vecuronium
verapamil
vigabatrin
viloxazine
warfarin
zotepine
Pregnancy Category
C
Breast Feeding
safe

REFERENCE: MICROMEDEX(R) Healthcare Series Vol. 111 expires 3/2002

DESIGNED BY HASHIM TAYEB (Bsc PHARM)